Though puede usarse para introducir un hecho establecido <though we have put men on the moon, we haven't stopped wars>, o una hipótesis o admisión de una posibilidad o probabilidad <though rain seemed likely, they decided to go anyway>.
Although suele ser intercambiable con though y puede introducir la afirmación de un hecho <although she ran her fastest race, she only received third prize>.
While significa though o although y generalmente aplica a cosas que ocurren al mismo tiempo <while the two were polite with each other, there was no longer much fondness between them>.